Regional adenosine-induced hypoperfusion without hyperenhancement on LGE-MRI in young HCM patients: comparison to subjects at risk of HCM and healthy volunteers
نویسندگان
چکیده
Background The relation between hypoperfusion and fibrosis is not completely understood in hypertrophic cardiomyopathy (HCM). One hypothesis is that hypoperfusion is a primary cause of fibrosis. Therefore, the aim of this study was to use cardiac magnetic resonance (CMR) to 1) measure if regional perfusion is decreased in young patients with HCM and in subjects at risk of HCM compared to normal controls and 2) determine if regional myocardial perfusion is decreased in areas with left ventricular hypertrophy (LVH) without detectable fibrosis.
منابع مشابه
Delayed contrast enhancement and perfusable tissue index in hypertrophic cardiomyopathy: comparison between cardiac MRI and PET.
UNLABELLED Delayed contrast enhancement (DCE) visualized by cardiac MRI (CMR) is a common feature in patients with hypertrophic cardiomyopathy (HCM), presumed to be related to myocardial fibrosis. The pathophysiologic basis of hyperenhancement in this patient group, however, remains unclear as limited histologic comparisons are available. The present study compares the perfusable tissue index (...
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